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No significant fetal ossification effects were seen in rabbits treated with oral doses approximately 7 times the human dose (the highest dose tested). However.1 of 14 litters were aborted and 1 of 14 litters were delivered prematurely.
Tell your doctor right away if you have any serious side effects.including. increased or cheap actonel 150 mg bone/joint/muscle pain.new or unusual hip/thigh/groin pain.jaw pain.eye/vision problems.
Because these adverse reactions are reported voluntarily from a population of uncertain size.it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Remind patients to give all of their healthcare providers an accurate medication history. Instruct patients to tell all of their healthcare providers that they are taking ACTONEL. Patients should be instructed that any time they have a medical problem they think may be from ACTONEL.they should talk to their doctor.
Dosing multiples provided above are based on the recommended human dose of 5 mg/day and normalized using body surface area (mg/m 2 ).
Figure 3. Change in BMD from Baseline Patients Recently Initiating Glucocorticoid Therapy.Actonel is a bisphosphonate used to strengthen bone.treat or prevent osteoporosis.and treat Paget’s disease of bone.
Jay W. Marks.MD.is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
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